Candida

[키워드] Acridine orange and Ethidium bromide Alter Amino acids CYSCystine Analysis AO/EBAcridine orange and Ethidium bromide approach binding binding free energy C. albican C. albicans Candida Candida albican carried cause cell membrane chronic Conditions obstructive pulmonary disease Clinical and Laboratory Standards Institute clinical study CLSIClinical and Laboratory Standards Institute complex Computational drug Concentration COPDchronic Conditions obstructive pulmonary disease Cystine demethylase diffusion Dimethyl sulfoxide disrupt DMSODimethyl sulfoxide docking method dose drug drug interaction Drug screening drugs Erg11pLanosterol 14-alpha demethylase FDAThe United States Food and Drug Administration fluorescent fungicidal fungicidal activity glycine GLYGlycine Health High-throughput virtual screening HISHistidine histidine HTVSHigh-throughput virtual screening humans In-vitro infect infections inhibitory concentration initial Interaction lanosterol Lanosterol 14-alpha demethylase MDSMolecular Dynamics Simulations MICMinimum inhibitory concentration Microscopy Minimum inhibitory concentration MMGBSAMolecular mechanics energies with generalized born surface area Molecular dynamics simulation molecular dynamics simulations Molecular mechanics energies with generalized born surface area mortality rate PBSPhosphate buffer saline PDBProtein Data Bank Phenylalanine PHEPhenylalanine Phosphate buffer saline Phosphatidylcholines Picoseconds POPCPhosphatidylcholines Protein Data Bank psPicoseconds repurposing Safe SDStandard deviation Serine SERSerine SPStandard-precision Standard deviation Standard-precision tested The United States Food and Drug Administration tyrosine TYRTyrosine Variable-dielectric surface generalized born model 2.0 VSGB 2.0Variable-dielectric surface generalized born model 2.0 XPXtra-precision Xtra-precision Yeast extract/peptone/dextrose YPDYeast extract/peptone/dextrose
[DOI] 10.1016/j.medidd.2022.100137 [Article Type] Research article